Generic Premarin Tablets
Premarin for oral administration contains a mixture of conjugated estrogens obtained exclusively from natural sources, occurring as the sodium salts of water-soluble estrogen sulfates blended to represent the average composition of material derived from pregnant mares' urine. It is a mixture of sodium estrone sulfate and sodium equilin sulfate. It contains as concomitant components, as sodium sulfate conjugates, 17ÃŽÂ±-dihydroequilin, 17ÃŽÂ±-estradiol, and 17ÃŽÂ²-dihydroequilin. Tablets for oral administration are available in 0.3 mg, 0.45 mg, 0.625 mg, 0.9 mg, and 1.25 mg strengths of conjugated estrogens.
Premarin 0.3 mg, 0.45 mg, 0.625 mg, 0.9 mg, and 1.25 mg tablets also contain the following inactive ingredients: calcium phosphate tribasic, carnauba wax, hydroxypropyl cellulose, hypromellose, lactose monohydrate, magnesium stearate, microcrystalline cellulose, polyethylene glycol, powdered cellulose, sucrose, and titanium dioxide.
Premarin tablets comply with USP Dissolution Test criteria as outlined below:
|Premarin 1.25 mg tablets||USP Dissolution Test 4|
|Premarin 0.3 mg, 0.45 mg and 0.625 mg tablets||USP Dissolution Test 5|
|Premarin 0.9 mg tablets||USP Dissolution Test 6|