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Topical minoxidil gel is for patients with pattern baldness. It is not intended for frontal baldness or a receding hairline. The mechanism by which minoxidil stimulates hair growth is not established, but possible mechanisms of action of minoxidil may include:
K+ATP-mediated stimulation of hair follicular cells by one of its sulphated active metabolites.
Prolongation of the anagen phase of hair and increase in the follicular size, thereby preventing premature entry into the telogen phase.
Improvement in local micro circulation.
All people may not be responsive to topical minoxidil treatment. The amount of hair regrowth differs from person to person. Although data suggest that those users who have been balding for a shorter period or who have a smaller area of baldness on the vertex are more likely to respond to topical minoxidil, individual responses cannot be predicted. It is unlikely anyone will be able to grow back all of his or her hair.